SEC FORM 13F-HR

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F COVER PAGE

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Report for the Calendar Year or Quarter Ended:12-31-2021
Check here if Amendment  Amendment Number:
This Amendment (Check only one.):  is a restatement.
  adds new holdings entries.
Institutional Investment Manager Filing this Report:
Name:M&T Bank Corp
Address:C/O CORPORATE REPORTING
ONE M&T PLAZA 5TH FLR
Buffalo, NY  14203
Form 13F File Number:028-00267

The institutional investment manager filing this report and the person by whom it is signed hereby represent that the person signing the report is authorized to submit it, that all information contained herein is true, correct and complete, and that it is understood that all required items, statements, schedules, lists, and tables, are considered integral parts of this form.

Person Signing this Report on Behalf of Reporting Manager:
Name:William J. Farrell
Title:Executive Vice President
Phone:302 636-6770
Signature, Place, and Date of Signing:
William J. FarrellWilmingtonDE01-28-2022
[Signature][City, State][Date]
Report Type (Check only one.):
X13F HOLDINGS REPORT. (Check here if all holdings of this reporting manager are reported in this report.)
  13F NOTICE. (Check here if no holdings reported are in this report, and all holdings are reported by other reporting manager(s).)
  13F COMBINATION REPORT. (Check here if a portion of the holdings for this reporting manager are reported in this report and a portion are reported by other reporting manager(s).)
Form 13F Summary Page
Report Summary:
Number of Other Included Managers:6
Form 13F Information Table Entry Total:8,688
Form 13F Information Table Value Total:23,802,533
(thousands)
List of Other Included Managers:
Provide a numbered list of the name(s) and Form 13F file number(s) of all institutional investment managers with respect to which this report is filed, other than the manager filing this report.
[If there are no entries in this list, state “NONE” and omit the column headings and list entries.]
No.Form 13F File NumberName
1028-03980Manufacturers & Traders Trust Company
3028-10909Wilmington Trust Investment Advisors, Inc.
7028-03740Wilmington Trust National Association
9028-03742Wilmington Trust Company
13028-06601Wilmington Trust Funds Management Corp.
14028-12629Wilmington Trust Investment Management, LLC